WRML.2017-03-01.WormFax-NAPfix is back-pic-Haemonchus-biosecurity-wedgies v drones

 WormFaxNSW – January 2017

The January issue is now up on the  web:


Many thanks to the labs at NSW DPI, EMAI (Kathy Cooper et al), and to Veterinary Health Research (now part of Invetus)), Armidale (Amanda Saunders et al) for supplying (every month, over many years), summary data on sheep WormTests around NSW.

NAPfix® is back (we have an OP-based drench again)

Australia has had an organophosphate-based sheep drench for over half a century, with an occasional gap in supply.

Naphthalophos (NAP) (“Rametin” (Bayer)) was one of the early ones.

In the last decade or two, we have had a few choices, e.g. pyraclifos (pyraclifos + albendazole (ABZ); “Colleague”(Coopers)), various brands of NAP in addition to Bayer’s “Rametin” (“Combat”(Virbac), and “Pole Vault”), and the NAP-based combination, NAPfix (NAP+abamectin+ABZ (Jurox)). And, for a time “Neguvon” (triclorphon (Bayer)), was available under permit for use in goats to control Haemonchus. (My connection with Neguvon began back in the ‘olden days’. In the late 1970s, the typical mix vets in Australia used to drench (stomach tube) horses was Neguvon (for bots), thiabendazole (the new BZ  ‘wonder’ drench (‘released in AU mid 1960s, for sheep etc), and piperazine).

OPs had a narrower safety index than many drenches, and so had to be used with care. However, they gave us another option, an active from a  different family, and were especially useful when used in combination with unrelated actives. Through the 90s and ‘noughties’ we particularly hoped that use of OPs would take some pressure off the ‘mectins’ (macrocyclic lactones).

By 2016, OP-based sheep drenches had become thin on the ground in AU. See here:


It appeared we would no longer have access to an OP drench unless NAPfix made a comeback, which it has just recently.

NAPfix was first released ~ 2012. See here: https://wormmailinthecloud.wordpress.com/2012/11/05/wrml-napfix-hendra-vaccine-and-a-vets-life/

According to a recent release from Jurox, NAPfix® was ‘subject to a voluntary non-urgent recall in 2014 due to issues with the dispersibility of the product’. (For your information a copy of the company’s release is attached. Undated; received 2017-02-28).


As always, discuss this information and the role of NAPfix on your property with your adviser.

As to cost, I am guessing the price of NAPfix will be in the same ballpark as other multi-active (triple and quadruple) combinations, but “I have no real visibility around this” (“going forward”).

Assume nothing when it comes to any drench product, including those containing the newest (novel) actives (monepantel and derquantel). Regularly monitor the efficacy of all anthelmintics.

It is good that the Australian sheep industry again has access to an organophosphate drench (as well as the other drench groups). Each producer will need to determine if NAPfix can be added to the suite of products effective on their property. At the very least, do a DrenchCheck if using NAPfix (or any product!). This involves a worm egg count (WEC) on or just before the day of drenching, and again 14 days later.   More information here. Seriously consider getting larval cultures/differentiations (‘wormtype’) done as well, even if egg counts at the day 14 WEC are relatively low.

The best is to set up a DrenchTest, where a series of different anthelmintic actives are tested. More information here.  You can test individual actives, and work out likely efficacies of multi-active combinations from there. (Use the Wormboss combination-drench-efficacy-calculator). (In the case of NAPfix, it might be hard now to get naphthalophos as a single active product (Rametin), and in the case of Startect, derquantel is not available on its own).




Constantinoiu C photos

Another photo (used with permission) from Dr Constantin Constantinoiu of James Cook University. Qld. In the last WormMail, we had one of an Haemonchus larva which ingested fluorescent bacteria. Great pic!   Here is another nice one from CC: Haemonchus on abomasal mucosa. (Please do not use the pic without permission from the owner).


Practical biosecurity hints when bringing home purchased cattle


A good summary/introduction by Dr Pat Kluver. Pat concludes by saying the article does not present an exhaustive list of recommendations, and suggests readers get the biosecurity app:  http://www.farmbiosecurity.com.au/farmbiosecurity-app/   ( I am about to check it out). PS. Pat mentions triclabendazole-based flukicides as part of an effective quarantine treatment when fluke might be an issue. Another option in cattle, similarly effective, are the injectable flukicides that contain nitroxynil + clorsulon. (As always, check the label, including withholding periods etc).


Image source: Apple

Wedgies v drones


My money is on the wedgies.

SL, Armidale  2017-03-01